Individuals who are unable to control their weight with just exercise and dieting may benefit from lipotropic fat-burning injections such as MICC (short for Methionine, Inositol and Choline and Cyanocobalamin (B12)) injections.

These lipotropic agents boost the natural detoxification process of the body by increasing fat metabolism, eliminating toxins and waste products and assisting liver functions. This is also helpful for people in whom the accumulation of fat hinders the normal metabolic process and balance of hormones which may lead to fatty deposits in the liver and coronary system. The components of MIC injection, other lipotropic agents, and their benefits are described below:


L-Methionine is among the eight essential amino acids and is one of the building blocks needed for protein synthesis in our body. L-Methionine can be found in dietary products such as meat, eggs, fish, dairy items, spinach, potatoes, Brazil nuts, cereal grains, and in sesame seeds. L-methionine plays a vital role in our health and is often used in the treatment of liver disease, copper poisoning and may have a role in the treatment of depression.

L-Methionine is useful for enhancing the metabolism and elimination of fat and also promotes antioxidant mediated cell defence mechanisms. Being an essential amino acid, it is necessary for the synthesis of cysteine and taurine, and many other phospholipids.


Inositol, previously considered a member of the vitamin B complex, is a carbohydrate that can be synthesized by our body. The majority of inositol synthesized in humans is derived from glucose mainly by the kidneys, and then the testicles as well as other tissues. Inositol functions as a mediator of signal transduction between cells in response to various hormones, neurotransmitters, and growth factors and is also important for osmoregulation. In nature, inositol can be found mainly in cantaloupes and oranges as well as in bananas, kidney beans, raisins, and peanuts. The benefits of inositol can be seen in the management of weight especially when it is used along with other B complex vitamins. It helps in the breakdown of fat by the liver and helps enhance the body’s metabolism.


Choline is another important nutrient produced by the liver but since it is often synthesized insufficiently, it is considered essential. Therefore, it must be supplemented through the diet as it is necessary for the proper function of liver, kidneys, and gallbladder. Choline can be supplemented mainly with soybeans and eggs and is also found in beef, liver, cauliflower, tofu, and almonds.

Choline is also an essential part of weight loss programs as it functions as a methyl donor and enhances the detoxification function of the liver. Additionally, both choline and inositol have been found to improve mental function, decrease depressive symptoms in patients.

Pyridoxine Hydrochloride (Vitamin B6)

Vitamin B6 may be used in addition to the MICC injection and helps regulate many important biochemical functions such as those involving the RBCs, immunity, central nervous system, metabolism, energy production and is needed for proper absorption of vitamin B12.

Cobalamin (Vitamin B12)

Vitamin B12 helps the liver efficiently break down fats and carbohydrates. Vitamin B12 also enhances mood, stabilizes blood sugar levels, and boosts energy.

These lipotropic agents are a great help for those trying to lessen body fat and are known to work best when taken along with weight reduction exercises and diet therapies.


  1. McCormick HM, Drill VA. Lipotropic effects of liver extract, vitamin B12 and choline. Proceedings of the Society for Experimental Biology and Medicine. 1950 Jul;74(3):626-30.
  2. Cole LK, Vance JE, Vance DE. Phosphatidylcholine biosynthesis and lipoprotein metabolism. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids. 2012 May 1;1821(5):754-61.
  3. Rinella ME, Elias MS, Smolak RR, Fu T, Borensztajn J, Green RM. Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet. Journal of lipid research. 2008 May 1;49(5):1068-76.
  4. Hasengschwandtner F. Injection lipolysis for effective reduction of localized fat in place of minor surgical lipoplasty. Aesthetic surgery journal. 2006 Mar 1;26(2):125-30.